Remote controlling of CAR-T cells and toxicity management: Molecular switches and next generation CARs

Remote controlling of CAR-T cells and toxicity management: Molecular switches and next generation CARs

Cell-based immunotherapies have been selected for the front-line cancer treatment approaches. Among them, CAR-T cells have shown extraordinary effects in hematologic diseases including chemotherapy-resistant acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymp...

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Bibliographic Details
Main Authors: Ehsan Moghanloo, Hasan Mollanoori, Mohsen Talebi, Salar Pashangzadeh, Fatemeh Faraji, Farimah Hadjilooei, Habibollah Mahmoodzadeh
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Translational Oncology
Subjects:
Remote controlling
CAR-T cells
Toxicity management
Molecular switches
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000620

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http://www.sciencedirect.com/science/article/pii/S1936523321000620

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