Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

Summary: Malignant tumors exhibit high degrees of genomic heterogeneity at the cellular level, leading to the view that subpopulations of tumor cells drive growth and treatment resistance. To examine the degree to which tumors also exhibit metabolic heterogeneity at the level of individual cells, we...

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Bibliographic Details
Main Authors: Yang Zhang, Christelle Guillermier, Thomas De Raedt, Andrew G. Cox, Ophelia Maertens, Dean Yimlamai, Mingyue Lun, Adam Whitney, Richard L. Maas, Wolfram Goessling, Karen Cichowski, Matthew L. Steinhauser
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305423