Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment
The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression. RNA interference mediated by siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific mRNAs. Therefore, c...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-05-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383515000301 |