Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction

BackgroundDiscoveries in the identification of transcription factors, growth factors and extracellular signaling molecules have led to the detection of downstream targets that modulate valvular tissue organization that occurs during development, aging, or disease. Among these, matricellular protein,...

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Bibliographic Details
Main Authors: Suniti Misra, Shibnath Ghatak, Ricardo A. Moreno-Rodriguez, Russell A. Norris, Vincent C. Hascall, Roger R. Markwald
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Fak
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.649862/full