Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling

Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling

Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand GDF6 as a novel melanoma oncogene showed GDF6-activated BMP signaling suppresses differentiation of melanoma cells. Previous studies have id...

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Bibliographic Details
Main Authors: Alec K Gramann, Arvind M Venkatesan, Melissa Guerin, Craig J Ceol
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
melanoma
melanocyte
neural crest
mitf
bmp signaling
zebrafish
Online Access:https://elifesciences.org/articles/50047

Internet

https://elifesciences.org/articles/50047

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