Zinc Binds to RRM2 Peptide of TDP-43

Transactive response DNA and RNA binding protein 43 kDa (TDP-43) is a highly conserved heterogeneous nuclear ribonucleoprotein (hnRNP), which is involved in several steps of protein production including transcription and splicing. Its aggregates are frequently observed in motor neurons from amyotrop...

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Bibliographic Details
Main Authors: Andrey V. Golovin, Francois Devred, Dahbia Yatoui, Andrei Yu. Roman, Arthur O. Zalevsky, Remy Puppo, Regine Lebrun, Francoise Guerlesquin, Philipp O. Tsvetkov
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9080