HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent Mechanisms

HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent Mechanisms

The E6 oncoproteins of high-risk human papillomaviruses (HPV) of genus alpha contain a short peptide sequence at the carboxy-terminus, the PDZ binding domain, with which they interact with the corresponding PDZ domain of cellular proteins. Interestingly, E6 proteins from papillomaviruses of genus be...

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Bibliographic Details
Main Authors: Benjamin Marx, Daliborka Miller-Lazic, John Doorbar, Slawomir Majewski, Kay Hofmann, Martin Hufbauer, Baki Akgül
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
human papillomavirus (HPV)
E6 oncoprotein
Syntenin-2
methylation
differentiation
phosphatidylinositol-4
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01724/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01724/full

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