The Role of Microglia in the Spread of Tau: Relevance for Tauopathies

Tauopathies are neurodegenerative diseases which course with the accumulation of Tau, mainly in neurons. In addition, Tau accumulates in a hyperphosphorylated and aggregated form. This protein is released into the extracellular space and spreads following a stereotypical pattern, inducing the develo...

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Bibliographic Details
Main Authors: Juan R. Perea, María Llorens-Martín, Jesús Ávila, Marta Bolós
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00172/full