The sweet side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

The sweet side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

Innate immunity represents the first line of defence against pathogens and plays key roles in activation and orientation of the adaptive immune response. The innate immune system comprises both a cellular and a humoral arm. Components of the humoral arm include soluble pattern recognition molecules...

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Bibliographic Details
Main Authors: Antonio eInforzato, Patrick C. Reading, Elisa eBarbati, Barbara eBottazzi, Cecilia eGarlanda, Alberto eMantovani
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Immunology
Subjects:
Glycosylation
Inflammation
pathogen recognition
pentraxins
PTX3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00407/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00407/full

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