On the explicit use of experimental images in high resolution cryo-EM refinement [version 2; peer review: 2 approved]
Single particle cryogenic electron microscopy (cryo-EM) is transforming structural biology by enabling the analysis of difficult macromolecular specimens, such as membrane proteins or large complexes with flexible elements, at near atomic resolution with an accuracy close to that of X-ray crystallog...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2019-11-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-665/v2 |