CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis

CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis

Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), abnormal cytokine levels, and the survival advantage of neoplastic progenitors over their normal counterparts, which leads to progressive disappearance of polyclonal hematopoiesis. CD47 is a surface g...

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Bibliographic Details
Main Authors: A. Nonino, J.M. Nascimento, C.C. Mascarenhas, J.F. Mazzeu, R.W. Pereira, R.H. Jacomo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Myeloproliferative disorders
Primary myelofibrosis
Hematopoietic stem cells
Neoplastic stem cells
Antigens
CD47
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100610&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100610&lng=en&tlng=en

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