Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis

Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis

Introduction. Paraoxonase 1 (PON1) is a multifunctional enzyme associated with high-density lipoprotein particles (HDL). It is a cellular antioxidant that hydrolyses oxidized macromolecules, especially low-density lipoproteins (ox-LDL). Because increased oxidative stress is believed to play a cru...

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Bibliographic Details
Main Authors: Grubiša Ivana, Otašević Petar, Dimković Nada, Nedeljković Ivana, Toljić Boško, Vučinić Nada
Format: Article
Language:English
Published: Serbian Medical Society 2013-01-01
Series:Srpski Arhiv za Celokupno Lekarstvo
Subjects:
paraoxonase 1
gene polymorphisms
oxidative stress
atherogenesis
Online Access:http://www.doiserbia.nb.rs/img/doi/0370-8179/2013/0370-81791310629G.pdf

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http://www.doiserbia.nb.rs/img/doi/0370-8179/2013/0370-81791310629G.pdf

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