The evolution of transcriptional repressors in the Notch signaling pathway: a computational analysis

Abstract Background The Notch signaling pathway governs the specification of different cell types in flies, nematodes and vertebrates alike. Principal components of the pathway that activate Notch target genes are highly conserved throughout the animal kingdom. Despite the impact on development and...

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Bibliographic Details
Main Author: Dieter Maier
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Hereditas
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41065-019-0081-0