Synphilin-1 Interacts with AMPK and Increases AMPK Phosphorylation

Synphilin-1 Interacts with AMPK and Increases AMPK Phosphorylation

A role for the cytoplasmic protein synphilin-1 in regulating energy balance has been demonstrated recently. Expression of synphilin-1 increases ATP levels in cultured cells. However, the mechanism by which synphilin-1 alters cellular energy status is unknown. Here, we used cell models and biochemica...

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Bibliographic Details
Main Authors: Tianxia Li, Jingnan Liu, Gongbo Guo, Bo Ning, Xueping Li, Guangjing Zhu, Dejun Yang, Timothy H. Moran, Wanli W. Smith
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
synphilin-1
AMPK
ATP
energy balance
protein interaction
Online Access:https://www.mdpi.com/1422-0067/21/12/4352

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https://www.mdpi.com/1422-0067/21/12/4352

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