A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS.

Plasmodium falciparum (P. falciparum) malaria remains a significant cause of mortality and morbidity throughout the world. Development of an effective vaccine would be a key intervention to reduce the considerable social and economic impact of malaria.We conducted a Phase Ia, non-randomized, clinica...

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Main Authors: Eoghan de Barra, Susanne H Hodgson, Katie J Ewer, Carly M Bliss, Kerrie Hennigan, Ann Collins, Eleanor Berrie, Alison M Lawrie, Sarah C Gilbert, Alfredo Nicosia, Samuel J McConkey, Adrian V S Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4270740?pdf=render