Early Death in Two Patients with Acute Promyelocytic Leukemia Presenting the bcr3 Isoform, FLT3-ITD Mutation, and Elevated WT1 Level

Early Death in Two Patients with Acute Promyelocytic Leukemia Presenting the bcr3 Isoform, FLT3-ITD Mutation, and Elevated WT1 Level

Despite major advances in the treatment of acute promyelocytic leukemia (APL), the problem of early death (ED) remains unsolved. Alongside the currently known clinical and hematological risk factors, prognostic significance has been attributed to internal tandem duplication mutations of the fms-like...

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Bibliographic Details
Main Authors: Marianna Greco, Giovanni Caocci, Antonio Ledda, Adriana Vacca, Marcella Arras, Ivana Celeghini, Giorgio La Nasa
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2013/896394

Internet

http://dx.doi.org/10.1155/2013/896394

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