Subcutaneous immunization against Leishmania major - infection in mice: efficacy of formalin-killed promastigotes combined with adjuvants Imunização subcutânea na infecção do camundongo pela Leishmania major: eficácia dos promastigotos mortos pela formalina combinada com adjuvantes

Subcutaneous immunization against Leishmania major - infection in mice: efficacy of formalin-killed promastigotes combined with adjuvants Imunização subcutânea na infecção do camundongo pela Leishmania major: eficácia dos promastigotos mortos pela formalina combinada com adjuvantes

Formalin-killed promastigotes (FKP) of Leishmania major, in combination with Montanide ISA 720 (MISA), BCG or alum were used in vaccination of an inbred murine model against cutaneous leishmaniasis (CL). Significant and specific increases in anti-FKP IgG responses were detected for both alum-FKP and...

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Bibliographic Details
Main Authors: Joshua M. Mutiso, John C. Macharia, Rosemary M. Mutisya, Evans Taracha
Format: Article
Language:English
Published: Universidade de São Paulo 2010-04-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Cutaneous leishmaniasis
Formalin-killed promastigotes (FKP) promastigotes
Montanide ISA 720 (MISA)
BCG
Alum
BALB/c mice
Immune responses
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652010000200006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652010000200006

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