Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.

Lyme carditis is an extracutaneous manifestation of Lyme disease characterized by episodes of atrioventricular block of varying degrees and additional, less reported cardiomyopathies. The molecular changes associated with the response to Borrelia burgdorferi over the course of infection are poorly u...

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Main Authors: Diego Barriales, Itziar Martín-Ruiz, Ana Carreras-González, Marta Montesinos-Robledo, Mikel Azkargorta, Ibon Iloro, Iraide Escobés, Teresa Martín-Mateos, Estibaliz Atondo, Ainhoa Palacios, Monika Gonzalez-Lopez, Laura Bárcena, Ana R Cortázar, Diana Cabrera, Ainize Peña-Cearra, Sebastiaan M van Liempd, Juan M Falcón-Pérez, Miguel A Pascual-Itoiz, Juana María Flores, Leticia Abecia, Aize Pellon, Maria Luz Martínez-Chantar, Ana M Aransay, Alberto Pascual, Felix Elortza, Edurne Berra, José Luis Lavín, Héctor Rodríguez, Juan Anguita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001062

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https://doi.org/10.1371/journal.pbio.3001062

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