Control of Genome Stability by EndoMS/NucS-Mediated Non-Canonical Mismatch Repair

Control of Genome Stability by EndoMS/NucS-Mediated Non-Canonical Mismatch Repair

The DNA repair endonuclease EndoMS/NucS is highly conserved in Archaea and Actinobacteria. This enzyme is able to recognize and cleave dsDNA carrying a mismatched base pair, and its activity is enhanced by the interaction with the sliding clamp of the replisome. Today, EndoMS/NucS has been establish...

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Bibliographic Details
Main Authors: Esmeralda Cebrián-Sastre, Isabel Martín-Blecua, Sonia Gullón, Jesús Blázquez, Alfredo Castañeda-García
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
EndoMS/NucS
non-canonical mismatch repair
genome stability
hypermutation
antibiotic resistance
Actinobacteria
Online Access:https://www.mdpi.com/2073-4409/10/6/1314

Internet

https://www.mdpi.com/2073-4409/10/6/1314

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