A computational approach to identifying gene-microRNA modules in cancer.

MicroRNAs (miRNAs) play key roles in the initiation and progression of various cancers by regulating genes. Regulatory interactions between genes and miRNAs are complex, as multiple miRNAs can regulate multiple genes. In addtion, these interactions vary from patient to patient and even among patient...

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Bibliographic Details
Main Authors: Daeyong Jin, Hyunju Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4303261?pdf=render