Perfringolysin O: The Underrated Clostridium perfringens Toxin?

Perfringolysin O: The Underrated Clostridium perfringens Toxin?

The anaerobic bacterium Clostridium perfringens expresses multiple toxins that promote disease development in both humans and animals. One such toxin is perfringolysin O (PFO, classically referred to as θ toxin), a pore-forming cholesterol-dependent cytolysin (CDC). PFO is secreted as a water-solubl...

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Bibliographic Details
Main Authors: Stefanie Verherstraeten, Evy Goossens, Bonnie Valgaeren, Bart Pardon, Leen Timbermont, Freddy Haesebrouck, Richard Ducatelle, Piet Deprez, Kristin R. Wade, Rodney Tweten, Filip Van Immerseel
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Toxins
Subjects:
cholesterol-dependent cytolysin
gas gangrene
myonecrosis
necrohemorrhagic enteritis
enterotoxaemia
calves
Online Access:http://www.mdpi.com/2072-6651/7/5/1702

Internet

http://www.mdpi.com/2072-6651/7/5/1702

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