FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma.

Allergic asthma is characterized by airway eosinophilia, increased mucin production and allergen-specific IgE. Fc gamma receptor IIb (FcgammaRIIb), an inhibitory IgG receptor, has recently emerged as a negative regulator of allergic diseases like anaphylaxis and allergic rhinitis. However, no studie...

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Bibliographic Details
Main Authors: Nilesh Dharajiya, Swapnil V Vaidya, Hiroki Murai, Victor Cardenas, Alexander Kurosky, Istvan Boldogh, Sanjiv A Sur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2825267?pdf=render