Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry

The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infect...

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Bibliographic Details
Main Authors: Parikshit Bagchi, Mauricio Torres, Ling Qi, Billy Tsai
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14967-w