Novel Associations of Nonstructural Loci with Paraoxonase Activity

Novel Associations of Nonstructural Loci with Paraoxonase Activity

The high-density-lipoprotein-(HDL-) associated esterase paraoxonase 1 (PON1) is a likely contributor to the antioxidant and antiatherosclerotic capabilities of HDL. Two nonsynonymous mutations in the structural gene, PON1, have been associated with variation in activity levels, but substantial inter...

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Bibliographic Details
Main Authors: Ellen E. Quillen, David L. Rainwater, Thomas D. Dyer, Melanie A. Carless, Joanne E. Curran, Matthew P. Johnson, Harald H. H. Göring, Shelley A. Cole, Sue Rutherford, Jean W. MacCluer, Eric K. Moses, John Blangero, Laura Almasy, Michael C. Mahaney
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Lipids
Online Access:http://dx.doi.org/10.1155/2012/189681

Internet

http://dx.doi.org/10.1155/2012/189681

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