Identification of novel interacting partners of Sirtuin6.

SIRT6 is a member of the Sirtuin family of histone deacetylases that has been implicated in inflammatory, aging and metabolic pathways. Some of its actions have been suggested to be via physical interaction with NFκB and HIF1α and transcriptional regulation through its histone deacetylase activity....

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Bibliographic Details
Main Authors: Oxana Polyakova, Satty Borman, Rachel Grimley, Jessica Vamathevan, Brian Hayes, Roberto Solari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519869?pdf=render