Radiosynthesis and Evaluation of 5-[I]Iodoindol-3-yl-β--Galactopyranoside as a β-Galactosidase Imaging Radioligand

The synthesis and investigation of 5-[ 125 I]iodoindol-3-yl-β- d -galactopyranoside ([ 125 I]IBDG) as a radioligand for single-photon emission computed tomography (SPECT) imaging of β-galactosidase expression are described. No-carrier-added [ 125 I]IBDG was synthesized by a radioiododestannylation a...

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Bibliographic Details
Main Authors: Marcian E. Van Dort, Kuei C. Lee, Christin A. Hamilton, Alnawaz Rehemtulla, Brian D. Ross
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2008-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2008.00020