MicroRNA‐221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling

MicroRNA‐221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling

Abstract As a prevalent tumor among women, breast cancer is still an incurable disease due to drug resistance. In this study, we report microRNA‐221 to have a significant effect on breast cancer resistance to adriamycin. The microRNA‐221 is elevated in tumor tissue compared with nearby nontumor samp...

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Bibliographic Details
Main Authors: Yingchun Yin, Xinmei Wang, Tangyue Li, Qi Ren, Liang Li, Xiaoyu Sun, Baohua Zhang, Xinyun Wang, Hongmei Han, Yangyang He, Zhen Cao, Xiaojie Sun, Ziqiang Zhou
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Cancer Medicine
Subjects:
adriamycin resistance
Akt/mTOR pathway
breast cancer
microRNA‐221
Online Access:https://doi.org/10.1002/cam4.2817

Internet

https://doi.org/10.1002/cam4.2817

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