Coenzyme Q supplementation in pulmonary arterial hypertension

Mitochondrial dysfunction is a fundamental abnormality in the vascular endothelium and smooth muscle of patients with pulmonary arterial hypertension (PAH). Because coenzyme Q (CoQ) is essential for mitochondrial function and efficient oxygen utilization as the electron carrier in the inner mitocho...

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Bibliographic Details
Main Authors: Jacqueline Sharp, Samar Farha, Margaret M. Park, Suzy A. Comhair, Erika L. Lundgrin, W.H. Wilson Tang, Robert D. Bongard, Marilyn P. Merker, Serpil C. Erzurum
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000822