SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis

SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis

Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. Reactive oxygen species (ROS), including free superoxide radicals, play important roles in colitis. However, the role of SOD1 in oxidati...

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Bibliographic Details
Main Authors: Jiyoung Hwang, Jing Jin, Sejin Jeon, Shin Hye Moon, Min Young Park, Do-Young Yum, Jeong Hyun Kim, Ji-Eun Kang, Mi Hee Park, Eui-Joong Kim, Jae-Gu Pan, Oran Kwon, Goo Taeg Oh
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
SOD1
ROS
Immune response
Acute colitis
BA SOD
p38-MAPK/NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309654

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http://www.sciencedirect.com/science/article/pii/S2213231720309654

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