Characteristic Eye Movements in Ataxia-Telangiectasia-Like Disorder: An Explanatory Hypothesis

Characteristic Eye Movements in Ataxia-Telangiectasia-Like Disorder: An Explanatory Hypothesis

ObjectiveTo investigate cerebellar dysfunctions and quantitatively characterize specific oculomotor changes in ataxia-telangiectasia-like disorder (ATLD), a rare autosomal recessive disease caused by mutations in the MRE11 gene. Additionally, to further elucidate the pathophysiology of cerebellar da...

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Bibliographic Details
Main Authors: Pamela Federighi, Stefano Ramat, Francesca Rosini, Elena Pretegiani, Antonio Federico, Alessandra Rufa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Neurology
Subjects:
ataxia-telangiectasia-like disorder
saccade hypermetria
granule cells
parallel fibers
Purkinje cells
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00596/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00596/full

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