Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging

BackgroundBrain reserve can be defined as the individual variation in the brain structural characteristics that later in life are likely to modulate cognitive performance. Late midlife represents a point in aging where some structural brain imaging changes have become manifest but the effects of cog...

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Bibliographic Details
Main Authors: Bryan J. Neth, Jonathan Graff-Radford, Michelle M. Mielke, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Robert I. Reid, Matthew L. Senjem, Val J. Lowe, Mary M. Machulda, Ronald C. Petersen, Clifford R. Jack Jr., David S. Knopman, Prashanthi Vemuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00355/full