Optimization of Production and Characterization of a Tandem Single Chain Fragment Variable (taFv) against Human Leptin Receptor and Anti-Human CD4

Optimization of Production and Characterization of a Tandem Single Chain Fragment Variable (taFv) against Human Leptin Receptor and Anti-Human CD4

Background: Leptin deficiency or dysfunction in leptin receptor (ObR) signaling may tend to resistance to autoimmune diseases. On the other hand, leptin receptors exist on many cells and therefore blocking all of them will probably result in unfavorable effects. Targeted ObR blocking on specific imm...

Full description

Bibliographic Details
Main Authors: Leila Momajadi, Sayyed Hamid Zarkesh-Esfahani, Mohammad Rabbani, Rahman Emamzadeh, Forouzan Safari, Arash Babaei
Format: Article
Language:fas
Published: Vesnu Publications 2015-12-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Leptin
Autoimmune disease
Optimization
Bispecific antibody
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/5077

Internet

http://jims.mui.ac.ir/index.php/jims/article/view/5077

Similar Items