Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse

Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse

Biological exploration of early biomarkers for chronic kidney disease (CKD) in (pre)diabetic individuals is crucial for personalized management of diabetes. Here, we evaluated two candidate biomarkers of incident CKD (sphingomyelin (SM) C18:1 and phosphatidylcholine diacyl (PC aa) C38:0) concerning...

Full description

Bibliographic Details
Main Authors: Jialing Huang, Marcela Covic, Cornelia Huth, Martina Rommel, Jonathan Adam, Sven Zukunft, Cornelia Prehn, Li Wang, Jana Nano, Markus F. Scheerer, Susanne Neschen, Gabi Kastenmüller, Christian Gieger, Michael Laxy, Freimut Schliess, Jerzy Adamski, Karsten Suhre, Martin Hrabe de Angelis, Annette Peters, Rui Wang-Sattler
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Metabolites
Subjects:
chronic kidney disease
prediabetes and type 2 diabetes
diabetic nephropathy
reduced kidney function
leptin receptor-deficient mouse
high-fat-diet
Online Access:https://www.mdpi.com/2218-1989/11/2/89

Internet

https://www.mdpi.com/2218-1989/11/2/89

Similar Items