UBA2 activates Wnt/β-catenin signaling pathway during protection of R28 retinal precursor cells from hypoxia by extracellular vesicles derived from placental mesenchymal stem cells

UBA2 activates Wnt/β-catenin signaling pathway during protection of R28 retinal precursor cells from hypoxia by extracellular vesicles derived from placental mesenchymal stem cells

Abstract Background Stem cell transplantation has been proposed as an alternative treatment for intractable optic nerve disorders characterized by irrecoverable loss of cells. Mesenchymal stem cells, with varying tissue regeneration and recovery capabilities, are being considered for potential cell...

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Bibliographic Details
Main Authors: Kyungmin Koh, Mira Park, Eun Soo Bae, Van-An Duong, Jong-Moon Park, Hookeun Lee, Helen Lew
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Stem Cell Research & Therapy
Subjects:
Exosome
hPMSCs
Optic nerve injury
Retinal precursor cells
UBA2
Wnt/β-catenin
Online Access:http://link.springer.com/article/10.1186/s13287-020-01943-w

Internet

http://link.springer.com/article/10.1186/s13287-020-01943-w

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