Maintaining maximal metabolic flux by gene expression control.

One of the marvels of biology is the phenotypic plasticity of microorganisms. It allows them to maintain high growth rates across conditions. Studies suggest that cells can express metabolic enzymes at tuned concentrations through adjustment of gene expression. The associated transcription factors a...

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Bibliographic Details
Main Authors: Robert Planqué, Josephus Hulshof, Bas Teusink, Johannes C Hendriks, Frank J Bruggeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6168163?pdf=render