Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling

The development of neurons in the peripheral nervous system is dependent on target-derived, long-range retrograde neurotrophic factor signals. The prevailing view is that target-derived nerve growth factor (NGF), the prototypical neurotrophin, and its receptor TrkA are carried retrogradely by early...

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Bibliographic Details
Main Authors: Mengchen Ye, Kathryn M Lehigh, David D Ginty
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33012