Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion.

The CA125 antigen is found in the serum of many patients with serous ovarian cancer and has been widely used as a disease marker. CA125 has been shown to be an independent factor for clinical outcome in this disease. In The Cancer Genome Atlas ovarian cancer project, MUC16 expression levels are freq...

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Bibliographic Details
Main Authors: Thapi D Rao, Huasong Tian, Xun Ma, Xiujun Yan, Sahityasri Thapi, Nikolaus Schultz, Nestor Rosales, Sebastien Monette, Amy Wang, David M Hyman, Douglas A Levine, David Solit, David R Spriggs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4429113?pdf=render