High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa

High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa

Abstract Background Combination antiretroviral therapy (cART) has significantly reduced HIV morbidity and mortality in both developed and developing countries. However, the sustainability of cART may be compromised by the emergence of viral drug resistance mutations (DRM) and the cellular persistenc...

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Bibliographic Details
Main Authors: Elizabeth M. Etta, Lufuno Mavhandu, Cecile Manhaeve, Keanan McGonigle, Patrick Jackson, David Rekosh, Marie-Louise Hammarskjold, Pascal O. Bessong, Denis M. Tebit
Format: Article
Language:English
Published: BMC 2017-07-01
Series:AIDS Research and Therapy
Subjects:
HIV drug resistance
Antiretroviral therapy
Peripheral blood mononuclear cells
Plasma
Rural South Africa
Online Access:http://link.springer.com/article/10.1186/s12981-017-0161-z

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http://link.springer.com/article/10.1186/s12981-017-0161-z

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