Illuminating the Role of Vpr in HIV Infection of Myeloid Cells

Vpr is a 14 kDa accessory protein conserved amongst extant primate lentiviruses that is required for virus replication in vivo. Although many functions have been attributed to Vpr, its primary role, and the function under selective pressure in vivo, remains elusive. The minimal importance of Vpr in...

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Bibliographic Details
Main Authors: Sarah Beth Nodder, Suryaram Gummuluru
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
HIV
Vpr
DDR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01606/full