Overcoming leukemia heterogeneity by combining T cell engaging bispecific antibodies

Background Leukemia represents about 5% of all human cancers. Despite advances in therapeutics, a substantial number of patients succumb to the disease. Several subtypes of leukemia are inherently more resistant to treatment despite intensive chemotherapy or targeted therapy.Methods Here we describe...

Full description

Bibliographic Details
Main Authors: Brian Alexander, Lajos Pusztai, David L Rimm, Priti Hegde, Mariya Rozenblit, Richard Huang, Natalie Danziger, Shakti Ramkissoon, Kim Blenman, Jeffrey S Ross
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001626.full