Extravillous trophoblast cells-derived exosomes promote Vascular Smooth Muscle Cell Migration

Background: Vascular smooth muscle cells (VSMCs) migration is a critical process during human uterine spiral artery (SpA) remodeling and a successful pregnancy. Extravillous trophoblast cells (EVT) interact with VSMC and enhance their migration, however, the mechanisms by which EVT remodel SpA remai...

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Bibliographic Details
Main Authors: Carlos eSalomon, Sarah eYee, Katherin eScholz, Kanchan eVaswani, David eKvaskoff, Miharu eKobayashi, Sebastian E Illanes, Murray David Mitchell, Gregory eRice
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00175/full