Effect of race, genetic population structure, and genetic models in two-locus association studies: clustering of functional renin-angiotensin system gene variants in hypertension association studies

Previous genetic association studies have overlooked the potential for biased results when analyzing different population structures in ethnically diverse populations. The purpose of the present study was to quantify this bias in two-locus association studies conducted on an admixtured urban populat...

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Bibliographic Details
Main Authors: A.C. Pereira, G.A. Mota, I. Benseñor, P.A. Lotufo, J.E. Krieger
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
ACE
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100008