Protective role of P2Y2 receptor against lung infection induced by pneumonia virus of mice.

ATP released in the early inflammatory processes acts as a danger signal by binding to purinergic receptors expressed on immune cells. A major contribution of the P2Y(2) receptor of ATP/UTP to dendritic cell function and Th2 lymphocyte recruitment during asthmatic airway inflammation was previously...

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Bibliographic Details
Main Authors: Gilles Vanderstocken, Els Van de Paar, Bernard Robaye, Larissa di Pietrantonio, Benjamin Bondue, Jean-Marie Boeynaems, Daniel Desmecht, Didier Communi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3503929?pdf=render