Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery

Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery

Alpha-synuclein positive-intracytoplasmic inclusions are the common denominators of the synucleinopathies present as Lewy bodies in Parkinson’s disease, dementia with Lewy bodies, or glial cytoplasmic inclusions in multiple system atrophy. These neurodegenerative diseases also exhibit cell...

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Bibliographic Details
Main Authors: Marie-Laure Arotcarena, Margaux Teil, Benjamin Dehay
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Parkinson’s disease
multiple system atrophy
synucleinopathy
α-synuclein
macroautophagy
chaperone-mediated autophagy
mitophagy
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/8/6/565

Internet

https://www.mdpi.com/2073-4409/8/6/565

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