Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs

Abstract Saponin-based adjuvants have been widely used to enhance humoral and cellular immune responses in many species, but their mode of action is not fully understood. A characterization of the porcine transcriptional response to Matrix-M was performed in vitro using lymphocytes, monocytes or mon...

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Bibliographic Details
Main Authors: Viktor Ahlberg, Bernt Hjertner, Per Wallgren, Stina Hellman, Karin Lövgren Bengtsson, Caroline Fossum
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-017-0437-2