Application of Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma

Application of Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma

Monoclonal antibody G250 (mAbG250) recognizes a determinant on carbonic anhydrase IX (CAIX). CAIX is expressed by virtually all renal cell carcinomas of the clear cell type (ccRCC), but expression in normal tissues is restricted. The homogeneous CAIX expression in ccRCC and excellent targeting capab...

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Bibliographic Details
Main Authors: Egbert Oosterwijk, Peter F. A. Mulders, Jeannette C. Oosterwijk-Wakka, Otto C. Boerman
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:International Journal of Molecular Sciences
Subjects:
CAIX
monoclonal antibody
G250
girentuximab
clear cell renal cell carcinoma
RCC
radioimmunotherapy
imaging
Online Access:http://www.mdpi.com/1422-0067/14/6/11402

Internet

http://www.mdpi.com/1422-0067/14/6/11402

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