Mitochondrially targeted compounds and their impact on cellular bioenergetics

Mitochondria are recognized as critical sites of localized injury in a number of chronic pathologies which has led to the development of organelle directed therapeutics. One of the approaches employed to target molecules to the mitochondrion is to conjugate a delocalized cation such as triphenylpho...

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Bibliographic Details
Main Authors: Colin Reily, Tanecia Mitchell, Balu K. Chacko, Gloria A. Benavides, Michael P. Murphy, Victor M. Darley-Usmar
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231712000146