The engineering principles of combining a transcriptional incoherent feedforward loop with negative feedback

Abstract Background Regulation of gene expression is of paramount importance in all living systems. In the past two decades, it has been discovered that certain motifs, such as the feedforward motif, are overrepresented in gene regulatory circuits. Feedforward loops are also ubiquitous in process co...

Full description

Bibliographic Details
Main Author: Gregory T. Reeves
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-019-0190-3