Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis
Abstract Background Klotho (KL) was originally characterized as an aging suppressor gene, and has been identified as a tumor suppressor gene in a variety of cancers, including colorectal cancer. Recent years have witnessed the importance of metabolism transformation in cancer cell malignancies maint...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-06-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-018-0241-2 |