Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis

Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis

Abstract Background Klotho (KL) was originally characterized as an aging suppressor gene, and has been identified as a tumor suppressor gene in a variety of cancers, including colorectal cancer. Recent years have witnessed the importance of metabolism transformation in cancer cell malignancies maint...

Full description

Bibliographic Details
Main Authors: Qingguo Li, Yaqi Li, Lei Liang, Jing Li, Dakui Luo, Qi Liu, Sanjun Cai, Xinxiang Li
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cell Communication and Signaling
Subjects:
Colorectal cancer
Klotho
Aerobic glycolysis
Online Access:http://link.springer.com/article/10.1186/s12964-018-0241-2

Internet

http://link.springer.com/article/10.1186/s12964-018-0241-2

Similar Items