Genetic Inhibition of sFRP3 Prevents Glial Reactivity in a Mouse Model of Accelerated Aging

Purpose Aging is the most significant risk factor for neurodegenerative disorders that are typified by cognitive deficits. Our recent work utilizing BubR1 hypomorphic (BubR1H/H) mice, an accelerated aging model, has revealed that genetic inhibition of the endogenous Wnt pathway inhibitor secreted fr...

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Bibliographic Details
Main Authors: Ana Mia Corujo-Ramirez, Malvika Dua, Ki Hyun Yoo, Alfredo Oliveros, Mi-Hyeon Jang
Format: Article
Language:English
Published: Korean Continence Society 2020-11-01
Series:International Neurourology Journal
Subjects:
Online Access:http://www.einj.org/upload/pdf/inj-2040436-218.pdf